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What is MDMA?

MDMA is a drug that can make people feel euphoric and empathetic. Molly is the street name for powder or crystal MDMA, often sold in capsules. Ecstasy is the street name for the pill form of MDMA.

As of 2016, MDMA has no accepted medical uses, but it is currently undergoing testing for use in the treatment of post-traumatic stress disorder.

Small doses of MDMA are used as an entheogen to enhance prayer or meditation by some religious practitioners. MDMA or Ecstasy is useful in psychotherapy, facilitating self-examination with reduced fear.

Molly vs Ecstasy vs MDMA

MDMA is the official chemical name for the pure chemical compound – in an ideal world, Molly would be 100% pure MDMA. Molly is a street name for MDMA in powder form, often contained in clear capsules. “Molly” doesn’t mean pure. Ecstasy is a street name for MDMA in pill/tablet form.

What are the effects of MDMA?

Side effects during use (perhaps ~7 hours)

“MDMA has been administered to more than 750 human subjects in clinical studies with only one single serious adverse event occurring as a result of the drug.” In this patient, “full recovery occurred 1 day after MDMA administration.”

  • Dry mouth
  • Difficulty concentrating
  • Anxiety
  • Feeling cold
  • Impaired balance/gait
  • Heavy legs
  • Jaw clenching/tight jaw
  • Lack of appetite
  • Perspiration
  • Thirst
  • Restless legs

Long-term side effects

MDMA researcher Matthew Baggott: “To the best of my understanding, doses around 1.5-1.7 mg/kg MDMA (roughly 100 to 125 mg MDMA) are unlikely to cause long-lasting serotonin changes. Studies by MAPS have looked for changes in mental abilities after people participated in their studies, with some participants receiving 125 mg followed by 62.5 mg, and have not found any changes.”

Short-term desirable effects, lasting for 3-4 h

  • Everything is perfect – with you and with the world
  • Euphoria (extreme happiness)
  • Empathy + increased ability to connect with others
  • A feeling that you are more able to be yourself / be authentic

Long-term desirable effects

  • Anecdotal reports that MDMA is effective in dealing with past trauma (and scientific support of MDMA helping PTSD in clinical settings)
  • Increased bonds with friends
  • A strengthened or enhanced romantic relationship

MDMA Medical uses

As of 2016, MDMA has no accepted medical uses, but it is currently undergoing testing for use in the treatment of post-traumatic stress disorder.

MAPS aims to make MDMA a prescription treatment for PTSD by 2021. Dr. Bronner’s has generously donated, though millions more in funding is needed.

Why is MDMA as a treatment for PTSD important?

“Since 2009, more U.S. soldiers have died from suicide than combat.”

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